Category: Health & Safety
Using Over-the-Counter Medications Safely
Over-the-counter medications, often called OTC medications, can be purchased without a prescription. They include products used for pain, fever, allergies, coughs, colds, heartburn, constipation, diarrhea, sleep problems, skin conditions, and many other common concerns.
Being available without a prescription does not mean a medication is risk-free. OTC products can cause side effects, interact with prescriptions, worsen certain medical conditions, or lead to an accidental overdose when they are used incorrectly.
Always read the complete label before taking an OTC medication, even if you have used the same brand before.
What Is an Over-the-Counter Medication?
An OTC medication is approved for people to select and use without an individual prescription when they follow the label directions.
OTC medications may be sold in:
- Pharmacies
- Grocery stores
- Convenience stores
- Warehouse stores
- Online pharmacies
- Other retail stores
They may come as:
- Tablets
- Capsules
- Liquids
- Chewable tablets
- Gummies
- Creams
- Ointments
- Sprays
- Drops
- Patches
- Suppositories
- Inhaled products
The same medication may be available in several forms and strengths. Do not assume that every version uses the same dose or directions.
Start by Identifying the Symptom
Before selecting a product, identify what you are trying to treat.
Ask yourself:
- What symptom do I have?
- How long has it been happening?
- How severe is it?
- Do I know what may have caused it?
- Do I have other symptoms?
- Have I already tried anything?
- Could this be an emergency?
- Do I have a health condition that affects which products are safe?
- Am I already taking medication for the same symptom?
OTC medication may provide temporary relief, but it may not treat the underlying cause.
If a symptom is severe, unusual, worsening, or lasting longer than expected, contact a healthcare professional.
Read the Drug Facts Label
OTC medications in the United States use a standardized Drug Facts label. The FDA requires important information to appear in a consistent format to help consumers compare and use products safely. FDA
The label includes:
- Active ingredient
- Purpose
- Uses
- Warnings
- Directions
- Other information
- Inactive ingredients
Read every section before taking the medication.
Active Ingredient
The active ingredient is the substance that produces the medication’s effect.
For example, a pain-relief product may contain:
- Acetaminophen
- Ibuprofen
- Naproxen
- Aspirin
- Another ingredient
The active ingredient is more important than the brand name.
Two products with different brand names may contain the same active ingredient. Taking both can result in an accidental overdose.
Before combining medications, compare the active ingredients on every label.
Purpose
The purpose section describes what the active ingredient does.
Examples include:
- Pain reliever
- Fever reducer
- Antihistamine
- Cough suppressant
- Decongestant
- Antacid
- Laxative
- Sleep aid
One product may contain several active ingredients with different purposes.
Uses
The uses section lists the symptoms the product is intended to treat.
Use the medication only for an approved or professionally recommended purpose. Do not assume that a product is appropriate simply because someone else used it for a similar problem.
If your symptom is not listed, ask a pharmacist or healthcare provider before using the product.
Warnings
The warnings section may explain:
- Who should not use the medication
- Which medical conditions require professional advice
- Possible interactions
- Serious side effects
- When to stop using it
- When to contact a provider
- Whether it may cause drowsiness
- Whether alcohol should be avoided
- Whether it is safe during pregnancy or breastfeeding
- How long the product may be used
Do not skip this section because you have taken the product before. Warnings and formulations may change, and your health or medication list may also have changed.
Directions
The directions explain:
- How much to take
- How often to take it
- The maximum amount
- How long to use it
- How to use the product
- Doses for different age groups
Follow the directions exactly unless a qualified healthcare professional gives you different instructions.
More medication does not provide faster or better relief. Taking too much can cause serious harm.
Other Information
This section may include:
- Storage instructions
- Temperature requirements
- Information about ingredients
- Safety seals
- Additional handling instructions
Store the medication according to the label.
Inactive Ingredients
Inactive ingredients may include:
- Colors
- Flavors
- Sweeteners
- Preservatives
- Coatings
- Fillers
- Binding agents
These ingredients do not produce the main medication effect, but they may matter if you have allergies, sensitivities, dietary restrictions, or difficulty swallowing certain forms.
Avoid Duplicate Active Ingredients
Accidental duplication is one of the biggest OTC medication risks.
A person might take:
- A pain reliever
- A cold-and-flu medication
- A nighttime cold product
- A sleep product
Several of those products may contain the same active ingredient.
Combination products are especially important to check because one dose may contain medication for pain, fever, cough, congestion, allergies, or sleep.
Do not combine products based only on their brand names or the symptoms listed on the front of the box.
Read the active ingredient section and ask a pharmacist:
“Do any of these products contain the same medication?”
Be Careful With Acetaminophen
Acetaminophen is found in many prescription and OTC products, including medications for:
- Pain
- Fever
- Colds
- Flu symptoms
- Sleep
- Headaches
It may also appear as “APAP” or another abbreviation on a prescription label.
Taking more than one acetaminophen-containing product can cause an accidental overdose and serious liver injury.
Before using a product containing acetaminophen:
- Check every medication you take.
- Follow the dose and timing instructions.
- Do not exceed the maximum amount listed or prescribed.
- Ask about safe use if you have liver disease.
- Ask about alcohol use.
- Contact a professional immediately if you may have taken too much, even if you feel well.
The FDA advises consumers to read every prescription and OTC label because acetaminophen can appear in hundreds of different products. FDA
Use Pain Relievers Carefully
Common OTC pain relievers include acetaminophen and nonsteroidal anti-inflammatory drugs, often called NSAIDs.
NSAIDs include medications such as:
- Ibuprofen
- Naproxen
- Aspirin
NSAIDs may not be appropriate for everyone.
Ask a healthcare professional before using them if you:
- Have kidney disease
- Have a history of stomach ulcers or bleeding
- Take a blood thinner
- Have certain heart conditions
- Have high blood pressure
- Have had a reaction to an NSAID
- Are pregnant
- Take other medications that affect bleeding or kidney function
Different pain relievers have different risks. Do not assume they can always be combined or substituted for one another.
Use Cold and Flu Products Carefully
Cold and flu products often contain several active ingredients.
A combination product may include:
- A pain reliever
- A fever reducer
- A cough suppressant
- An expectorant
- A decongestant
- An antihistamine
- A sedating ingredient
Choose a product that treats the symptoms you actually have. Taking a multi-symptom product may expose you to medication you do not need.
Check for:
- Duplicate ingredients
- Drowsiness warnings
- Blood pressure warnings
- Age restrictions
- Alcohol warnings
- Driving restrictions
- Maximum length of use
Cold medication may relieve symptoms, but it does not automatically treat the cause of the illness.
Decongestants May Not Be Safe for Everyone
Decongestants are used for nasal congestion but may affect heart rate, blood pressure, sleep, or urination.
Ask a pharmacist or healthcare provider before using a decongestant if you have:
- High blood pressure
- Heart disease
- Thyroid disease
- Diabetes
- Glaucoma
- Prostate or urination problems
- Another relevant condition
They may also interact with certain prescription medications.
Do not use a decongestant longer than the label allows.
Antihistamines Can Cause Drowsiness
Antihistamines are used for allergies and are included in some cold and sleep products.
Some can cause:
- Drowsiness
- Dizziness
- Confusion
- Dry mouth
- Blurred vision
- Difficulty urinating
- Increased fall risk
Do not drive, operate equipment, or combine the medication with alcohol or other sedating substances until you understand how it affects you.
Older adults and people taking several medications may be more sensitive to certain antihistamines.
Ask a pharmacist to help you compare products.
Sleep Aids Require Caution
OTC sleep aids may contain sedating antihistamines or other ingredients.
They can cause:
- Morning drowsiness
- Confusion
- Dizziness
- Falls
- Dry mouth
- Difficulty urinating
- Reduced alertness
- Interactions with other sedating medications or substances
An OTC sleep product is not a long-term solution for an ongoing sleep disorder.
Speak with a healthcare provider if:
- Sleep problems continue
- You need the product frequently
- You snore loudly
- You wake up gasping
- You fall asleep during daytime activities
- Sleep problems began after a medication change
- Anxiety, depression, pain, or another health concern is interfering with sleep
Stomach, Constipation, and Diarrhea Products
OTC products may temporarily help with:
- Heartburn
- Gas
- Nausea
- Constipation
- Diarrhea
However, these symptoms can also be caused by infection, medication, food intolerance, dehydration, or another medical condition.
Ask for professional guidance if symptoms:
- Are severe
- Continue or repeatedly return
- Include blood
- Are associated with significant pain
- Cause dehydration
- Begin after a new medication
- Are accompanied by unexplained weight loss
- Affect a young child, older adult, or medically vulnerable person
Some antacids, laxatives, and diarrhea medications can interact with prescriptions or affect how other medications are absorbed.
Use Liquid Medication Correctly
Use the measuring device provided with the product or recommended by a pharmacist.
Use:
- An oral syringe
- A dosing cup
- A medication spoon
- Another properly marked device
Do not use an ordinary kitchen spoon. Household spoons are not reliable measuring devices.
Pay attention to units such as:
- Milliliters
- Teaspoons
- Milligrams per milliliter
Shake the product if the label says “shake well.”
If you do not understand how much to measure, ask the pharmacist to demonstrate.
Do Not Use Adult Medication for a Child Without Guidance
Children are not simply smaller adults. The correct medication and dose may depend on:
- Age
- Weight
- Medical history
- Other medication
- The specific product
- The medication concentration
Do not estimate a child’s dose by dividing an adult dose.
Use only products labeled for the child’s age and follow the directions carefully. Ask a pediatric healthcare professional or pharmacist when you are unsure.
Keep all medication out of children’s reach and sight.
Pregnancy and Breastfeeding
Some OTC medications may not be appropriate during pregnancy or breastfeeding.
Before using a product, ask:
- An obstetric healthcare professional
- The child’s pediatric provider
- A pharmacist
- Another qualified healthcare professional
Do not assume a product is safe because it is natural, topical, or available without a prescription.
Tell the pharmacist how far along the pregnancy is and whether you are breastfeeding.
Medical Conditions Can Change What Is Safe
Ask a pharmacist or healthcare provider before using an OTC medication if you have:
- Kidney disease
- Liver disease
- Heart disease
- High blood pressure
- Diabetes
- Glaucoma
- Asthma
- A bleeding disorder
- Stomach ulcers
- Difficulty urinating
- Seizure disorder
- Another chronic condition
A product that is appropriate for one person may be unsafe for another.
Check for Medication Interactions
An OTC medication may interact with:
- Prescriptions
- Other OTC products
- Vitamins
- Supplements
- Alcohol
- Cannabis
- Certain foods
- Medical conditions
Bring or show the pharmacist an updated list of everything you take.
Ask:
“Is this safe with my current medications?”
“Could this make me drowsy?”
“Could it affect my blood pressure?”
“Should I take it at a different time from my other medication?”
Do not rely entirely on an online interaction checker. A pharmacist can consider your complete medication list and health history.
Supplements and Herbal Products Are Different
Vitamins, minerals, and herbal products are often sold near OTC medications, but they are regulated differently.
“Natural” does not mean harmless.
Supplements can:
- Cause side effects
- Interact with medications
- Affect bleeding
- Affect blood pressure
- Change test results
- Be unsafe during pregnancy
- Create problems before surgery
- Contain different amounts than expected
Tell your healthcare providers and pharmacist about every supplement you use.
Do not use a supplement as a substitute for prescribed treatment without discussing it with a qualified professional.
Avoid Using Someone Else’s Medication
Do not take an OTC product simply because another person says it worked for them.
The other person may have:
- Different symptoms
- Different medical conditions
- A different medication list
- A different appropriate dose
- A different risk of side effects
Read the label and make a decision based on your own health needs.
Do Not Use Medication Longer Than Directed
The label may limit how many days a product should be used.
Continuing longer can:
- Increase side effects
- Hide a worsening condition
- Cause dependence or rebound symptoms
- Delay diagnosis
- Create medication-related harm
If symptoms continue beyond the label’s recommended period, contact a healthcare professional.
Stop and Ask for Help When Something Seems Wrong
Stop using the product and seek professional guidance if:
- You develop a rash or swelling
- You experience unusual dizziness
- You become confused
- You have new difficulty breathing
- The symptom becomes worse
- A new symptom appears
- You take more than directed
- You accidentally combine duplicate ingredients
- You are unsure whether the medication caused a reaction
Call 911 for a severe allergic reaction, serious breathing difficulty, unconsciousness, seizure, or another life-threatening emergency.
What to Do if You Take Too Much
If you may have taken too much medication:
- Do not take another dose.
- Keep the container with you.
- Contact Poison Control or emergency services.
- Follow the instructions you receive.
- Do not make yourself vomit unless specifically told to do so.
- Do not wait for symptoms if the product can cause delayed harm.
In the United States, Poison Control can be reached at 1-800-222-1222.
Call 911 immediately if the person:
- Is unconscious
- Cannot be awakened
- Has severe difficulty breathing
- Is having a seizure
- Shows another life-threatening symptom
Store OTC Medication Safely
Keep medication:
- In its original container
- With the label attached
- Away from children and pets
- Away from heat and moisture
- At the temperature listed
- Separate from another person’s medication
- Secure if it could be misused
Do not transfer medication into an unlabeled bag or container.
Check expiration dates and dispose of expired or unneeded products according to pharmacy, FDA, or local instructions.
Helpful Resources: Browse Safe Storage for products, equipment, services, or supplies related to this section.
Ask the Pharmacist
A pharmacist can help you:
- Choose between products
- Compare active ingredients
- Avoid duplicates
- Check interactions
- Understand dosing
- Measure liquid medication
- Identify side effects
- Find options that cause less drowsiness
- Choose a medication appropriate for your health conditions
- Decide when you should contact a doctor
You do not need a prescription to ask a pharmacist a question.
Bring the products to the pharmacy counter or show clear photographs of the labels.
A Simple OTC Medication Checklist
Before buying:
- Identify the symptom.
- Read the active ingredient.
- Read the uses.
- Read every warning.
- Check your other medications.
- Confirm the correct age and dose.
- Ask a pharmacist if you are unsure.
Before taking:
- Confirm the product is for you.
- Check the dose.
- Check the time since your last dose.
- Use the correct measuring device.
- Confirm that you are not duplicating an ingredient.
- Follow food, alcohol, and driving warnings.
After taking:
- Watch for side effects.
- Do not take another dose too soon.
- Stop when directed.
- Contact a professional if symptoms continue.
- Seek immediate help for a serious reaction or overdose.
Suggested Guides
- Understanding Prescriptions & Medication Labels
- Filling a Prescription & Using a Pharmacy
- Managing Multiple Medications Safely
- Keeping Track of Health Information
- Knowing Which Health Changes to Discuss With Your Doctor
- Choosing Between Your Doctor, Urgent Care & the Emergency Room
Important Health & Safety Notice
The information in this guide is provided for general educational purposes only. Independence Answers is not a medical provider, and this content is not a substitute for professional medical advice, diagnosis, treatment, or supervision. Always follow the instructions of your doctor, pharmacist, or other qualified healthcare professional, especially if you have a medical condition, take medication, or are unsure whether an action is safe for you.
Do not ignore or delay seeking professional care because of something you read here. If you believe someone may be experiencing a serious or life-threatening emergency, call 911 or your local emergency number immediately.
